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oltipraz
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CYP2B6
SULT1E1
HSPA1A
NQO1
AKR7A3
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Pathway Enrichment
Most Correlated Biogroups
heterocyclic compound binding
organic cyclic compound binding
organic cyclic compound metabolic process
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
heterocycle metabolic process
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Curated Studies
Most Correlated Studies
Phytochemical-mediated responses in human hepatocytes.
Livers of rats treated with BNF, D3T, and OLT
Livers of rats treated with dithiolethione analogs D3T, OLT, or TBD
Livers from NRF2-null mice treated with oltipraz
Hepatocytes isolated from rats and treated with 29 ToxCast chemicals in a dose-dependent manner
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Literature
Most Relevant Literature
Effect of Oltipraz on urethral healing: An experimental study.
Efficacy of oltipraz in preventing acetaminophen-induced liver injury in mice.
Protective effect of oltipraz in testicular ischaemia/reperfusion injury: An experimental study.
Activation of Nrf2 signaling by oltipraz inhibits death of human macrophages with mycobacterium tube…
Drug-induced liver injury: Oltipraz and C2-ceramide intervene HNF-1α/GSTA1 expression via JNK signal…
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Clinical Trials
Most Relevant Clinical Trials
Oltipraz in the Prevention of Lung Cancer in People Who Smoke
Efficacy and Safety of Oltipraz in the Patients With Liver Fibrosis and Cirrhosis
Oltipraz for Liver Fat Reduction in Patients With Non-alcoholic Fatty Liver Disease Except for Liver…
Efficacy and Safety of Oltipraz in the Patients With Non-alcoholic Fatty Liver Disease
Efficacy and Safety of Oltipraz for Liver Fat Reduction in Patients With Non-Alcoholic Fatty Liver D…
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