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QuickView for oxazines (compound)


Genetic Markers

Most Correlated Genes

  1. EGR1
  2. FOS
  3. DEPP1
  4. CYP26B1
  5. KLHL24
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Pathway Enrichment

Most Correlated Biogroups

  1. heterocyclic compound binding
  2. organic cyclic compound binding
  3. organic cyclic compound metabolic process
  4. heterocycle metabolic process
  5. cytosol
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Curated Studies

Most Correlated Studies

  1. PI3K and PARP1 pathway co-targeting in BRCA1-mutant breast cancer cells
  2. Treated keratinocyte HaCaT cell line overexpressing EGFR, RELA (p65), or HRAS-VAL12D
  3. Oncogenic PI3K mutations in cancer cells following growth factor deprivation
  4. Preimplantation mouse embryos wih Oct4, Sall4 or Nanog knockdown
  5. Acute myeloid lymphoma cell lines treated with SYK inhibitor R406
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Literature

Most Relevant Literature

  1. Medicinal chemistry of oxazines as promising agents in drug discovery.
  2. Diastereoselective α-C-H functionalization of aliphatic N-heterocycles: an efficient route to ring f…
  3. ¹¹C]-(+)-PHNO PET imaging of dopamine D(2/3) receptors in Parkinson's disease with impulse control d…
  4. Rhodium-catalyzed transannulation of N-sulfonyl-1,2,3-triazoles and epoxides: regioselective synthes…
  5. Computational insights on the isomerization of photochromic oxazines.
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Clinical Trials

Most Relevant Clinical Trials

  1. Nicotine Metabolizers and [11C]-(+)-PHNO
  2. Dopamine Release in the Human Brain Following Alcohol Administration
  3. Concurrent PET D2/D3 Receptor Imaging and fMRI Smoking Cue Reactivity in Smokers
  4. Impact of Early Optimization of Brain Oxygenation on Neurological Outcome After Severe Traumatic Bra…
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