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oxazolidinones
(compound)
NextBio Summary
General Info
Genetic Markers
Most Correlated Genes
MAOA
HTR1B
HTR1D
CCL4
SAA2
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Pathway Enrichment
Most Correlated Biogroups
response to other organism
response to bacterium
regulation of immune response
positive regulation of immune response
defense response to other organism
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Curated Studies
Most Correlated Studies
Lungs of mice infected with methicillin resistant Staphylococcus aureus and treated with linezolid
Whole blood from S. aureus infected mice treated with linezolid or vancomycin
Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
Drug target sets for approved compounds
Broad Connectivity Map (CMAP 2.0) compound database
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Literature
Most Relevant Literature
In Situ Generated Zinc(II) Catalyst for Incorporation of CO2 into 2-Oxazolidinones with Propargylic …
Enantiopure synthesis of dihydrobenzo[1,4]-oxazine-3-carboxylic acids and a route to benzoxazinyl ox…
Oxazolidinones as Anti-tubercular Agents: Discovery, Development and Future Perspectives.
Evaluation of the monoamine oxidases inhibitory activity of a small series of 5-(azole)methyl oxazol…
Drug-drug interactions and safety of linezolid, tedizolid, and other oxazolidinones.
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Clinical Trials
Most Relevant Clinical Trials
Safety and Efficacy Study of Oxazolidinone to Treat Pneumonia
Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections
Tedizolid Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via I…
Single Dose Escalation and Multiple Dose Escalation Trial of an Intravenous Formulation of MRX-4
Single Dose Escalation and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4
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