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p21 activated kinases
(compound)
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Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Embryonic fibroblasts lincRNA-p21- null or wildtype treated or untreated with doxorubicin
Hepatocellular carcinoma HepG2 cells with siRNA knockdown of the nuclear protein WEE1
HCT116 colorectal carcinoma cells in the presence and absence of tumor suppressor PTEN
Fibroblast IMR-90 cells treated with gamma-radiation
Renal epithelial cells of PKD2 mutant and wildtype rats
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Literature
Most Relevant Literature
p21-activated kinases and gastrointestinal cancer.
PAKs in human disease.
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
p21-activated kinase 1: PAK'ed with potential.
The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP…
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Clinical Trials
Most Relevant Clinical Trials
Research of Biomarkers of Activity and Efficacy of BIBW2992 in Untreated Non-metastatic HNSCC Patien…
A Study to Assess Disease Activity in Adult Participants With Axial Spondyloarthritis Who Receive Up…
This Is The First Study Using Escalating Doses Of PF-03758309, An Oral Compound, In Patients With Ad…
Intracavitary Cisplatin-Fibrin Localized Chemotherapy After P/D or EPP for Malignant Pleural Mesothe…
KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia
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