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panobinostat
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Summary
General Info
Genetic Markers
Most Correlated Genes
DHRS2
SPINK2
CCDC184
SLC17A7
NR4A3
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Pathway Enrichment
Most Correlated Biogroups
heterocycle metabolic process
cellular aromatic compound metabolic process
organic cyclic compound metabolic process
nucleoplasm
heterocyclic compound binding
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Curated Studies
Most Correlated Studies
Glioblastoma cells from MYC[T58A] DN-TP53 mice treated with panobinostat
Acute lymphoblastic Leukemia SEM, KOPN-8, REH or Jurkat cells treated with panobinostat
Neuroblastoma in mice expressing human MYCN treated with histone deacetylase inhibitor panobinostat
Neuroepithelial progenitors differentiated from ESCs and treated with toxicants
Multiple myeloma cell lines treated with panobinostat, 5-Azacytidine, or N-methylpyrrolidone
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Literature
Most Relevant Literature
A novel treatment strategy utilizing panobinostat for high-risk and treatment-refractory hepatoblast…
Therapeutic potential of targeting Nrf2 by panobinostat in pituitary neuroendocrine tumors.
Outcomes with panobinostat in heavily pretreated multiple myeloma patients.
Identifying drug targets with thermal proteome profiling using IBT-16plex.
Targeting mitochondrial energetics reverses panobinostat- and marizomib-induced resistance in pediat…
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Clinical Trials
Most Relevant Clinical Trials
A Panobinostat Presurgery
PDR001 + Panobinostat for Melanoma and NSCLC
Study of Panobinostat in Patients With Neuroendocrine Tumors
Panobinostat Biological Correlates Study
Study of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid Tumors
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