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pladienolide b
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Summary
General Info
Genetic Markers
Most Correlated Genes
TAP1
CYP26A1
CARTPT
TGM2
PRSS1
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Pathway Enrichment
Most Correlated Biogroups
MANNO_MIDBRAIN_NEUROTYPES_HENDO
RNA binding
heterocycle metabolic process
heterocyclic compound binding
organic cyclic compound binding
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Lateral plate mesoderm APLRN+ cells differentiated from ESCs and treated with pladienolide B
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Most Relevant Literature
Enantioselective total synthesis of pladienolide B: a potent spliceosome inhibitor.
Synthesis of a pladienolide B analogue with the fully functionalized core structure.
Synthesis of the macrocyclic core of (-)-pladienolide B.
Increase in pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P…
Stereochemistry of pladienolide B.
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A Dose Escalation Study of E7107 Administered Intravenously on Days 1 and 8 Every 21 Days to Patient…
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