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poly ADP- ribose) polymerase- 1
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General Info
Curated Studies
Most Correlated Studies
Lymphoblastoid B cells treated with olaparib to inhibit poly(ADP-ribose) polymerase (PARP)
Prostate stromal WPMY1 cells grown in complete or androgens-deprived media with or without Olaparib
Burkitt lymphoma DG-75 cells expressing EBV LMP1 and treated with olaparib
Ovarian cancer cells resistant to Olaparib or shRNA-mediated CEBPB knockdown
Cervical cancer HeLa cells with PARP-1 siRNA knockdown
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Literature
Most Relevant Literature
The role of PARP1 in neurodegenerative diseases and aging.
Deacetylation-dependent regulation of PARP1 by SIRT2 dictates ubiquitination of PARP1 in oxidative s…
PARP1 Inhibition and Effect on Burn Injury-Induced Inflammatory Response and Cardiac Function.
Nuclear Tkt promotes ischemic heart failure via the cleaved Parp1/Aif axis.
Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone …
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Clinical Trials
Most Relevant Clinical Trials
A Study to Assess the Safety and Pharmacokinetics of an Inhibitor of Poly ADP-Ribose Polymerase-1 (P…
Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagno…
An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as…
Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Sub…
A Study Of Poly (ADP-Ribose) Polymerase Inhibitor PF-01367338 In Combination With Several Chemothera…
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