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poly i
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Summary
General Info
Genetic Markers
Most Correlated Genes
CXCL10
IFIT1
CCL5
RSAD2
IFIT3
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Pathway Enrichment
Most Correlated Biogroups
HALLMARK_INTERFERON_GAMMA_RESPONSE
GSE42021_TREG_VS_TCONV_PLN_UP
GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN
GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_UP
GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN
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Curated Studies
Most Correlated Studies
Transplanted HCmel3 mouse melanomas relapsing post adoptive T-cell (ACT) therapy
Macrophages from chronic hepatitis C patients ex vivo treated with poly(I.C)
Bronchial and nasal epithelial cells from asthma and rhinitis patients
Whole blood of IRAK4-null, MYD88-null and normal donors treated with Toll-like receptor agonists
Dendritic cells (CD8 positive) stimulated with TLR3 ligand polyIC for 2, 6 or 18hr
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Literature
Most Relevant Literature
Polyinosinic acid decreases sequestration and improves systemic therapy of measles virus.
Aβ potentiates inflammatory activation of glial cells induced by scavenger receptor ligands and infl…
A double-blind, placebo-controlled, randomized, clinical trial of the TLR-3 agonist rintatolimod in …
Signaling through Toll-like receptor 3 and Dectin-1 potentiates the capability of human monocyte-der…
Polyinosinic acid enhances delivery of adenovirus vectors in vivo by preventing sequestration in liv…
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Clinical Trials
Most Relevant Clinical Trials
ARREST - A Phase I Study of SABR for Poly-metastatic Disease
Phase I Oncovir Poly IC:LC and NY-ESO-1/gp100
Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma
Polyinosinic-Polycytidylic Acid-poly-L-lysine Carboxymethylcellulose (Poly-ICLC) in Healthy Voluntee…
A Phase I, Open-label Study to Assess the Safety and Efficacy of Poly-ICLC Plus Nivolumab in Unresec…
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