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QuickView for polyq (compound)
Most Correlated Studies
- Contribution of Nuclear and Extranuclear PolyQ to Huntington’s Disease
- Cerebelli from mice with progressively larger HTT polyQ knockins from age 2 to 10 months
- Muscle gene expression profiles in 3 mouse models of spinal bulbar muscular atrophy (SBMA)
- Quadriceps muscle transcriptional profile in spinal bulbar muscular atrophy mouse model
- Drosophila gene expression during aging regulated by ubiquitous expression of polyglutamine Atrophin
Most Relevant Literature
- Autophagy preferentially degrades non-fibrillar polyQ aggregates.
- Predicting the involvement of polyQ- and polyA in protein-protein interactions by their amino acid c…
- Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila in…
- Disrupted nuclear import of cell cycle proteins in Huntington's/PolyQ disease causes neurodevelopmen…
- Binding structures of SERF1a with NT17-polyQ peptides of huntingtin exon 1 revealed by SEC-SWAXS, NM…
Most Relevant Clinical Trials
- A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Particip…
- Integrated Functional Evaluation of the Cerebellum
- Efficacy, Safety and Tolerability of AFQ056 in Patients With Huntington's Disease in Reducing Chorea
- Natural History of Oculomotor Neurophysiology in Ataxic and Pre-ataxic Carriers of SCA3/MJD
- Clinical Trial Readiness for SCA1 and SCA3
