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premature termination codons
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Genetic Markers
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Curated Studies
Most Correlated Studies
Colorectal cancer HCT116 cells treated with bafilomycin A1
Jag1K295*/+ as a mouse model for Alagille syndrome
Cervical carcinoma HeLa cells with shRNA knockdown and rescue of UPF1, SMG6, and SMG7 target genes
Intraductal carcinoma in situ of breast HDQ-P1 cells treated with immunomodulatory drug Y-320
Nonsense-mediated mRNA decay-inhibited LCLs from families predisposed to breast cancer
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Literature
Most Relevant Literature
When a ribosome encounters a premature termination codon.
Read-through therapy for mitochondrial DNA nonsense mutations.
Suppression of premature termination codons as a therapeutic approach.
Sense from nonsense: therapies for premature stop codon diseases.
Rationalization and prediction of selective decoding of pseudouridine-modified nonsense and sense co…
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Clinical Trials
Most Relevant Clinical Trials
Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mu…
Azithromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Poly…
Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Poly…
Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyp…
Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Nonsense Mutation Patients
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