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QuickView for proguanil (compound)


Genetic Markers

Most Correlated Genes

  1. TAF15
  2. ESR1
  3. MT1F
  4. ABCA1
  5. PRRG1
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Pathway Enrichment

Most Correlated Biogroups

  1. BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
  2. KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP
  3. REACTOME_CHOLESTEROL_BIOSYNTHESIS
  4. DACOSTA_UV_RESPONSE_VIA_ERCC3_DN
  5. HORTON_SREBF_TARGETS
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Curated Studies

Most Correlated Studies

  1. Broad Connectivity Map (CMAP 2.0) compound database
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Literature

Most Relevant Literature

  1. Unanticipated CNS Safety Signal in a Placebo-Controlled, Randomized Trial of Co-Administered Atovaqu…
  2. Histopathological and ultrastructural assessment of atovaquone-proguanil hydrochloride combination i…
  3. Atovaquone/Proguanil Resistance in an Imported Malaria Case in Chile.
  4. Proguanil synergistically sensitizes ovarian cancer cells to olaparib by increasing DNA damage and i…
  5. Revisiting the mode of action of the antimalarial proguanil using the yeast model.
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Clinical Trials

Most Relevant Clinical Trials

  1. The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in…
  2. Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunt…
  3. Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and Clopidogrel
  4. Drug Combinations of Atovaquone-Proguanil (AP) With ACT
  5. Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaqu…
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