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proguanil
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
TAF15
ESR1
MT1F
ABCA1
PRRG1
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Pathway Enrichment
Most Correlated Biogroups
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP
REACTOME_CHOLESTEROL_BIOSYNTHESIS
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN
HORTON_SREBF_TARGETS
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
Broad Connectivity Map (CMAP 2.0) compound database
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Literature
Most Relevant Literature
On the potential for discontinuing atovaquone-proguanil (AP) ad-hoc post-exposure and other abbrevia…
Amplicon Deep Sequencing Reveals Multiple Genetic Events Lead to Treatment Failure with Atovaquone-P…
Unanticipated CNS Safety Signal in a Placebo-Controlled, Randomized Trial of Co-Administered Atovaqu…
Uptake and usage of proguanil as malaria chemoprophylaxis and the socio-economic determinants of pro…
Artemether-lumefantrine, mefloquine and atovaquone-proguanil in the treatment of uncomplicated Plasm…
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Clinical Trials
Most Relevant Clinical Trials
The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in…
Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunt…
Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and Clopidogrel
Drug Combinations of Atovaquone-Proguanil (AP) With ACT
Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaqu…
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