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pten protein, human
(compound)
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Genetic Markers
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No genes found
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Functional Target of the Tumor Suppressor PTEN
Diffuse large B-cell lymphoma (DLBCL) and PTEN expression
T-ALL DND41 cell line Dexamethasone treated after PTEN knockdown
T-ALL cells and cell lines treated with PI3K inhibitor AS605240
Prostate tumor tissues from castrated mice with prostate-specific PTEN knockout
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Literature
Most Relevant Literature
Lysosomes Promote Cancer Metastasis via Exosome in PTEN-Deficient Tumors.
Vascular adaptation to cancer beyond angiogenesis: The role of PTEN.
Mosaicism in PTEN-new case and comment on the literature.
Development of informant-report neurobehavioral survey scales for PTEN hamartoma tumor syndrome and …
The potential role of PTEN inhibition in septic cardiomyopathy.
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Clinical Trials
Most Relevant Clinical Trials
A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With …
Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes
Nab-paclitaxel and Alpelisib for the Treatment of Anthracycline Refractory Triple Negative Breast Ca…
PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK…
Vevorisertib (ARQ 751) (4440-001) as a Single Agent or in Combination With Other Anti-Cancer Agents,…
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