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pxr receptor
(compound)
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Genetic Markers
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Curated Studies
Most Correlated Studies
Liver from mice treated with PXR or CAR ligands
Livers exposed to CAR agonist TCPOBOP or PXR agonist pregnenolone 16alpha-carbonitrile
PXR-dependent and independent mechanisms of liver toxicity
Hepatocellular carcinoma HepaRG cells with gene knockout of PXR
Livers of humanized CAR and PXR knockin or knockout mice treated with phenobarbital
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Literature
Most Relevant Literature
Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl h…
RXRα, PXR and CAR xenobiotic receptors mediate the apoptotic and neurotoxic actions of nonylphenol i…
Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Andros…
Pharmacokinetic-pharmacodynamic modeling of rifampicin-mediated Cyp3a11 induction in steroid and xen…
An insulin-like growth factor 1 receptor inhibitor induces CYP3A4 expression through a pregnane X re…
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Clinical Trials
Most Relevant Clinical Trials
The Role of the Pregnane X Receptor (PXR) in Indole Signaling and Intestinal Permeability in Inflamm…
Effects of Pregnane X Receptor (PXR) Activation on Human Glucose, Lipid and Hormone Homeostasis
Pregnane X Receptor (PXR) Agonist Rifampicin Effects on Glucose, Lipid and Hormone Homeostasis
Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions
The Effects of PXR Activation on Hepatic Fat Content
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