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QuickView for saquinavir (compound)


Genetic Markers

Most Correlated Genes

  1. CCL2
  2. DBP
  3. PLAU
  4. MCM4
  5. PRKCI
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. organic cyclic compound metabolic process
  5. heterocycle metabolic process
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Curated Studies

Most Correlated Studies

  1. Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Codelink]
  2. Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Affymetrix]
  3. Broad Connectivity Map (CMAP 2.0) compound database
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Literature

Most Relevant Literature

  1. Enhancement of cellular uptake, transport and oral absorption of protease inhibitor saquinavir by na…
  2. Structural Basis of Why Nelfinavir-Resistant D30N Mutant of HIV-1 Protease Remains Susceptible to Sa…
  3. Nanoemulsion-based intranasal drug delivery system of saquinavir mesylate for brain targeting.
  4. Saquinavir Induced Suicidal Death of Human Erythrocytes.
  5. Effects of resveratrol on P-glycoprotein and cytochrome P450 3A in vitro and on pharmacokinetics of …
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Clinical Trials

Most Relevant Clinical Trials

  1. A 48-Week, Randomised, Study to Describe the Pharmacokinetic Profile and Durability of Atazanavir-Sa…
  2. Bioequivalence Study of Generic GPO Saquinavir and Norvir® Versus Invirase® and Norvir®
  3. BASIC: Boosted Atazanavir or Saquinavir Induced Lipid Changes
  4. A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patient…
  5. The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-Infected Pregnant Women.
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