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QuickView for saquinavir (compound)


Genetic Markers

Most Correlated Genes

  1. CCL2
  2. DBP
  3. PLAU
  4. MCM4
  5. PRKCI
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. organic cyclic compound metabolic process
  5. heterocycle metabolic process
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Curated Studies

Most Correlated Studies

  1. Broad Connectivity Map (CMAP 2.0) compound database
  2. Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Affymetrix]
  3. Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Codelink]
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Literature

Most Relevant Literature

  1. Microenvironmental pH modifying films for buccal delivery of saquinavir: Effects of organic acids on…
  2. The Significance of Utilizing In Vitro Transfer Model and Media Selection to Study the Dissolution P…
  3. Enhancement of cellular uptake, transport and oral absorption of protease inhibitor saquinavir by na…
  4. Structural Basis of Why Nelfinavir-Resistant D30N Mutant of HIV-1 Protease Remains Susceptible to Sa…
  5. Nanoemulsion-based intranasal drug delivery system of saquinavir mesylate for brain targeting.
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Clinical Trials

Most Relevant Clinical Trials

  1. A 48-Week, Randomised, Study to Describe the Pharmacokinetic Profile and Durability of Atazanavir-Sa…
  2. Bioequivalence Study of Generic GPO Saquinavir and Norvir® Versus Invirase® and Norvir®
  3. BASIC: Boosted Atazanavir or Saquinavir Induced Lipid Changes
  4. A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patient…
  5. The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-Infected Pregnant Women.
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