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QuickView for sb203580 (compound)


Genetic Markers

Most Correlated Genes

  1. DHRS2
  2. S100A2
  3. SERPINA3
  4. MUC4
  5. ID1
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Pathway Enrichment

Most Correlated Biogroups

  1. cytosol
  2. cell periphery
  3. response to organic substance
  4. regulation of nitrogen compound metabolic process
  5. AACTTT_UNKNOWN
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Curated Studies

Most Correlated Studies

  1. Monocyte-derived dendritic cells treated with MEK inhibitor U0126 or p38/MAPK inhibitor SB203580
  2. Acute monocytic leukemia (AML) THP-1 cells HIV gp120 or LPS stimulated following SB203580 treatment
  3. Colon cancer SW480 cells expressing BOP1, CSK2 or NFIL3 treated with different kinase inhibitors
  4. Burkitt lymphoma BL-2 cells and tonsil B cells with kinase/enzyme inhibitor treatments
  5. Embryonic and induced pluripotent stem cells maintained in naive or primed states
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Literature

Most Relevant Literature

  1. p38 MAPK inhibitor SB203580 enhances anticancer activity of PARP inhibitor olaparib in a synergistic…
  2. SB203580 protects against inflammatory response and lung injury in a mouse model of lipopolysacchari…
  3. SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mi…
  4. The p38 MAPK inhibitor, SB203580, inhibits cell invasion by Neospora caninum.
  5. Decisive role of water and protein dynamics in residence time of p38α MAP kinase inhibitors.
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Clinical Trials

Most Relevant Clinical Trials

  1. Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer
  2. Immune Cell Response to Stimuli
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