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QuickView for secretases (compound)
Most Correlated Studies
- Brown adipose tissues of mice fed high sugar/fat diet and treated with BACE1 inhibitor RO5508887
- Liver tissues from rats after treatment with different compounds
- L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
- L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
Most Relevant Literature
- In silico study of selected alkaloids as dual inhibitors of β- and γ-secretases for Alzheimer's dise…
- The emerging role of β-secretases in cancer.
- New precision medicine avenues to the prevention of Alzheimer's disease from insights into the struc…
- Secretases in Alzheimer's disease: Novel insights into proteolysis of APP and TREM2.
- Amylin and Secretases in the Pathology and Treatment of Alzheimer's Disease.
Most Relevant Clinical Trials
- Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi Sarcoma
- Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer
- Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients Wit…
- BCMA-Specific CAR T-Cells Combined With a Gamma Secretase Inhibitor (JSMD194) to Treat Relapsed or P…
- Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive…
