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QuickView for shiga toxin 2 (compound)


Genetic Markers

Most Correlated Genes

  1. CXCL8
  2. ATF3
  3. ACKR3
  4. GDF15
  5. PMAIP1
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Pathway Enrichment

Most Correlated Biogroups

  1. BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
  2. LEE_BMP2_TARGETS_DN
  3. HALLMARK_TNFA_SIGNALING_VIA_NFKB
  4. WEI_MYCN_TARGETS_WITH_E_BOX
  5. NAGASHIMA_NRG1_SIGNALING_UP
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Curated Studies

Most Correlated Studies

  1. Microvascular endothelial cells response to Shiga toxins
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Literature

Most Relevant Literature

  1. Cognitive Deficits Found in a Pro-inflammatory State are Independent of ERK1/2 Signaling in the Muri…
  2. Eliglustat prevents Shiga toxin 2 cytotoxic effects in human renal tubular epithelial cells.
  3. Gene expression profile and injury sites in mice treated with Shiga toxin 2 and lipopolysaccharide a…
  4. Seropositivity to Shiga toxin 2 among Argentinian urban and rural residents. Association with sociod…
  5. Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues inv…
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of Chimeric Monoclonal Antibodies to Shiga Toxins 1 and 2
  2. Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection
  3. Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion
  4. Anti-Shiga Toxin Hyperimmune Equine Immunoglobulin F(ab')2 Fragment (INM004) in Healthy Volunteers
  5. Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU
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