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Curated Studies

Most Correlated Studies

  1. Colon cancer HT 115 cells expressing UGT1A isoform 2 shRNA and treated with SN-38
  2. Colorectal cancer drug-sensitive parental cell lines and chemotherapy-resistant sub cell lines
  3. HepaRG cells as a model of the primary human hepatocyte transcriptome
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Literature

Most Relevant Literature

  1. Redox-sensitive irinotecan liposomes with active ultra-high loading and enhanced intracellular drug …
  2. Combination chemotherapy consisting of irinotecan, etoposide, and carboplatin for refractory or rela…
  3. Development of a physiologically based pharmacokinetic model to predict irinotecan disposition durin…
  4. Development of an LC-MS/MS Method for Measurement of Irinotecan and Its Major Metabolites in Plasma:…
  5. All You Need to Know About UGT1A1 Genetic Testing for Patients Treated With Irinotecan: A Practition…
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Clinical Trials

Most Relevant Clinical Trials

  1. Liposomal SN-38 in Treating Patients With Metastatic Colorectal Cancer
  2. Liposomal SN-38 in Treating Patients With Small Cell Lung Cancer
  3. Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in P…
  4. EZN-2208 (Pegylated SN-38) in Combination With Bevacizumab in Refractory Solid Tumors
  5. UGT1A1 Combined With Pharmacokinetics of SN-38 in CPT-11-based CRT in Patients With Advanced Rectal …
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