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temsirolimus
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Summary
General Info
Genetic Markers
Most Correlated Genes
COL11A1
ERAP2
LDB2
ATN1
DKK1
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
cytosol
organic cyclic compound binding
heterocyclic compound binding
cell periphery
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Curated Studies
Most Correlated Studies
Ovarian carcinoma A2780 cells treated with temsirolimus and cisplatin-resistant A2780-CP20 cells
Brain of SCA3 transgenic or wildtype mice after treatment with rapamycin ester CCI-779
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
A phase II study of bevacizumab and temsirolimus in advanced extra-pancreatic neuroendocrine tumors.
Combinatory anti-tumor activities of 1,4-bis[2-(dimethylamino)ethylamino]-5,8-dihydroxyanthracene-9,…
Combined treatment with crizotinib and temsirolimus is an effective strategy in mantle cell lymphoma…
Therapeutic Efficacy of Temsirolimus in a Patient-derived Model of Metastatic Fibrolamellar Hepatoce…
PECAM-1 mediates temsirolimus-induced increase in neutrophil transendothelial migration that leads t…
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Clinical Trials
Most Relevant Clinical Trials
Erlotinib and Temsirolimus for Solid Tumors
Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors
Study of Temsirolimus, Topotecan, and Bortezomib
Temsirolimus In Phase 0
Doxil, Bevacizumab and Temsirolimus Trial
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