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tlr8 protein, human
(compound)
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Genetic Markers
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No genes found
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Whole blood of IRAK4-null, MYD88-null and normal donors treated with Toll-like receptor agonists
Macrophage development from common myeloid progenitor cells in response to CSF1 and R848
Macrophages IFNg primed from PBMC treated with Ro60-associated ssRNA (hY3) complex
Monocytes from systemic juvenile idiopathic arthritis patients treated with lipopolysaccharide
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Literature
Most Relevant Literature
Human toll-like receptor 8 (TLR8) in NK cells: Implication for cancer immunotherapy.
Selecting Therapeutic Antisense Oligonucleotides with Gene Targeting and TLR8 Potentiating Bifunctio…
Molecular docking of SARS-COV-2 Spike epitope sequences identifies heterodimeric peptide-protein com…
Further hit optimization of 6-(trifluoromethyl)pyrimidin-2-amine based TLR8 modulators: Synthesis, b…
Human TLR8 induces inflammatory bone marrow erythromyeloblastic islands and anemia in SLE-prone mice…
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Clinical Trials
Most Relevant Clinical Trials
TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurre…
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Dam…
Bacteremia in Intensive Care Unit (ICU)
VTX-2337 and Pegylated Liposomal Doxorubicin (PLD) in Patients With Recurrent or Persistent Epitheli…
PF-07225570 Alone or in Combination With an Anti-PD-1 Antibody in Recurrent Non-muscle Invasive Blad…
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