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tripeptidyl peptidase 1
(gene)
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General Info
Body Atlas
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Granulocyte-macrophage progenitor cell of bone marrow
Macrophage of peripheral blood
Microglial cell
Monocyte of peripheral blood
Myeloid cells of peripheral blood
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A mouse mutant deficient in both neuronal ceroid lipofuscinosis-associated proteins CLN3 and TPP1.
Tripeptidyl Peptidase 1 Regulates Human Trophoblast Cell Proliferation Implying a Role in Placentati…
Generation of pathogenic TPP1 mutations in human stem cells as a model for neuronal ceroid lipofusci…
Elevated levels of tripeptidyl peptidase 1 do not ameliorate pathogenesis in a mouse model of Alzhei…
TPP1 Delivery to Lysosomes with Extracellular Vesicles and their Enhanced Brain Distribution in the …
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Clinical Trials
Most Relevant Clinical Trials
Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients
A Safety, Tolerability, and Efficacy Study of Intracerebroventricular BMN 190 in Pediatric Patients …
A Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics, and…
A Multicenter, Multi-national Open-label Program to Provide BMN 190 to Patients Diagnosed With CLN2 …
A Multicenter, Multinational, Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 1…
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