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trypanocidal drugs
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CTGF
RRM2
HSPA6
THBS1
ATF3
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Pathway Enrichment
Most Correlated Biogroups
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
PILON_KLF1_TARGETS_DN
heterocyclic compound binding
organic cyclic compound binding
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Curated Studies
Most Correlated Studies
Clear cell renal cell carcinoma 786-O cells treated with pentamidine
D. melanogaster embryos Smaug mutant, free or polysome associated mRNAs
C. elegans L1 larvae exposed to EtBr and/or serial UVC radiation
Podocytes differentiated and treated with puromycin aminonucleoside or adriamycin
Drug induced injuries across different tissues in rats
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Literature
Most Relevant Literature
Evaluating 5-nitrofurans as trypanocidal agents.
Modelling appropriate use of trypanocides to restrict wide-spread multi-drug resistance during chemo…
Is trypanocidal drug resistance a threat for livestock health and production in endemic areas? Food …
Validation of ligands targeting metacaspase-2 (MCA2) from Trypanosoma brucei brucei and their applic…
Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities …
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Clinical Trials
Most Relevant Clinical Trials
A Trial Testing Amiodarone in Chagas Cardiomiopathy
Atorvastatin on Inflammation and Cardiac Function in Chronic Chagas Disease
CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)
Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' Disease
Short-course Benznidazole Treatment to Reduce Trypanosoma Cruzi Parasitic Load in Women of Reproduct…
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