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QuickView for tunicamycin (compound)


Genetic Markers

Most Correlated Genes

  1. DDIT3
  2. NUPR1
  3. HSPA5
  4. INHBE
  5. CRELD2
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Pathway Enrichment

Most Correlated Biogroups

  1. PUJANA_BRCA1_PCC_NETWORK
  2. FISCHER_DREAM_TARGETS
  3. cytosol
  4. KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
  5. KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN
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Curated Studies

Most Correlated Studies

  1. Endoplasmic reticulum stress in PERK liver specific knockouts
  2. Livers from mice deficient for IRE1 and XBP1
  3. Immortalized B cell lines under endoplasmic retriculum stress
  4. Gene expression changes induced in wild-type or Atf6a-/- mice by tunicamycin treatment
  5. Cancer cell lines exposed to disulfide bond inhibitors or anoxic conditions
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Literature

Most Relevant Literature

  1. Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor.
  2. Tunicamycin: chemical synthesis and biosynthesis.
  3. Involvement of Sec71 and Ubp2 in tunicamycin-induced ER stress response in the fission yeast.
  4. Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in Candida albicans.
  5. Tunicamycin induced endoplasmic reticulum stress in the small intestine.
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Clinical Trials

Most Relevant Clinical Trials

  1. Mechanisms of Cell Death in Spinal Muscular Atrophy
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