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tyrphostins
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
DHRS2
CRIP1
AGR2
XIST
SPRR3
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
organic cyclic compound binding
heterocyclic compound binding
organic cyclic compound metabolic process
heterocycle metabolic process
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Curated Studies
Most Correlated Studies
Prostate cancer mouse models treated with different compounds
Expression data from human cytomegalovirus(HMCV)-infected human monocytes: role of EGFR
Colorectal cancer cell lines treated with inhibitors of signaling pathway effectors
L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Tyrphostin AG1024 downregulates aryl hydrocarbon receptor (AhR) expression in an IGF1R and IR-indepe…
Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Protea…
Inhibition of tyrosine kinase signaling by tyrphostin AG126 downregulates the IL-21/IL-21R and JAK/S…
Tyrphostin RG14620 selectively reverses ABCG2-mediated multidrug resistance in cancer cell lines.
Tyrphostin AG-related compounds attenuate H2O2-induced TRPM2-dependent and -independent cellular res…
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Clinical Trials
Most Relevant Clinical Trials
Phase 1 Clinical Study to Describe Biological Safety and Pharmacokinetics of Tyrphostin
STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastati…
AflacST1901: Peds WP1066
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