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u0126
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NextBio Summary
General Info
Genetic Markers
Most Correlated Genes
EGR1
DUSP6
ETV5
FOS
CYP1B1
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Pathway Enrichment
Most Correlated Biogroups
heterocyclic compound binding
organic cyclic compound metabolic process
organic cyclic compound binding
heterocycle metabolic process
KOBAYASHI_EGFR_SIGNALING_24HR_DN
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Curated Studies
Most Correlated Studies
Monocyte-derived dendritic cells treated with MEK inhibitor U0126 or p38/MAPK inhibitor SB203580
Prostate cancer DU145 cells expressing ETS1 shRNA or undergoing U0126 treatment
NIH-3T3 mouse embryonic fibroblasts expressing RasV12 treated with interferon-alpha or U0126
Mammary gland cancer after SHP2 knockout or SHP2 signaling inhibition
Fibroblasts treated with U0126 and insulin
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Literature
Most Relevant Literature
An Addition of U0126 Protecting Heart Grafts From Prolonged Cold Ischemia-Reperfusion Injury in Hear…
mTOR inhibitor temsirolimus and MEK1/2 inhibitor U0126 promote chromosomal instability and cell type…
Single-cell heterogeneity in suppression of PC12 differentiation by direct microinjection of a diffe…
U0126 protects cells against oxidative stress independent of its function as a MEK inhibitor.
U0126 attenuates cerebral vasoconstriction and improves long-term neurologic outcome after stroke in…
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Clinical Trials
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There were no clinical trials for u0126
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