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QuickView for veliparib (compound)


Genetic Markers

Most Correlated Genes

  1. CRIP1
  2. MAL
  3. NPR3
  4. LCN2
  5. S100A2
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. cytosol
  3. organic cyclic compound binding
  4. heterocyclic compound binding
  5. organic cyclic compound metabolic process
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Curated Studies

Most Correlated Studies

  1. Breast cancer cerebral xenografts treated with carboplatin and ABT888
  2. Prostate cancer LNCaP cells treated with PARP inhibitors and with PARP1/PARP2 siRNA knockdown
  3. Cystic fibrosis bronchial epithelial cells expressing mutant CFTR and treated with small molecules
  4. L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
  5. L1000 CMAP - Bone marrow CD34 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Veliparib for the treatment of solid malignancies.
  2. Efficacy and safety of veliparib plus chemotherapy for the treatment of lung cancer: A systematic re…
  3. Tooth Formation as Experimental Model to Study Chemotherapy on Tissue Development: Effect of a Speci…
  4. NCI 7977: A Phase I Dose-Escalation Study of Intermittent Oral ABT-888 (Veliparib) plus Intravenous …
  5. Effect of PARP-1 Inhibition on Rotator Cuff Healing: A Feasibility Study Using Veliparib in a Rat Mo…
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Clinical Trials

Most Relevant Clinical Trials

  1. Liposomal Irinotecan and Veliparib in Treating Patients With Solid Tumors
  2. Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Pat…
  3. Expanded Access to Veliparib
  4. Pre-Operative Radiation and Veliparib for Breast Cancer
  5. To Evaluate the Safety of Veliparib in Combination With Temozolomide in Subjects With Solid Tumors
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