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QuickView for vemurafenib (compound)


Genetic Markers

Most Correlated Genes

  1. SPRY4
  2. DUSP6
  3. UCN2
  4. CEMIP
  5. ETV4
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Pathway Enrichment

Most Correlated Biogroups

  1. KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
  2. FISCHER_DREAM_TARGETS
  3. DODD_NASOPHARYNGEAL_CARCINOMA_DN
  4. GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP
  5. PUJANA_CHEK2_PCC_NETWORK
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Curated Studies

Most Correlated Studies

  1. Normal dermal fibroblast and malignant melanoma cells treated with BRAF inhibitor vemurafenib
  2. Melanoma UACC62 cells with vemurafenib drug resistance
  3. Malignant melanoma A375 cells treated with BRAF inhibitor vemurafenib
  4. Melanoma A-375 cells treated with tretinoin and vemurafenib alone or in combination
  5. Melanoma WM989 cells sorted by variable EGFR expression after treatment with vemurafenib
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Literature

Most Relevant Literature

  1. A Quality by Design Approach for Developing SNEDDS Loaded with Vemurafenib for Enhanced Oral Bioavai…
  2. Long-Term Real-World Outcomes and Safety of Vemurafenib and Vemurafenib + Cobimetinib Therapy in Pat…
  3. INTRAVITREAL METHOTREXATE IN VEMURAFENIB-INDUCED UVEITIS.
  4. Erdheim-Chester disease and vemurafenib: a review of ophthalmic presentations and clinical outcomes.
  5. Vemurafenib inhibits the replication of diabetogenic enteroviruses in intestinal epithelial and panc…
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of Vemurafenib, Carboplatin, and Paclitaxel
  2. A Study of Vemurafenib in Participants With Metastatic Melanoma
  3. ML29255 Neoadjuvant Vemurafenib and Cobimetinib Melanoma
  4. Vemurafenib Plus Cobimetinib in Metastatic Melanoma
  5. Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma
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