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Correlation Engine 2.0
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(e.g. rs3825942, IGF1, nitric oxide metabolic process, Breast Cancer, Adipose tissue)
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QuickView for positive regulation of kinase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Pituitary gland
  2. Kidney medulla
  3. Lung
  4. Dorsal root ganglia
  5. Prefrontal cortex
Explore Body Atlas Results

Disease Atlas

Most Correlated Diseases

  1. Alpha-1-antitrypsin deficiency
  2. Disorder of digestive system
  3. Disease due to Orthopoxvirus
  4. Perforation of tympanic membrane
  5. Bacterial infection due to Bacillus
Explore Disease Atlas Results

Pharmaco Atlas

Most Correlated Compounds

  1. ARQ 197
  2. CGP 60474
  3. FR 180204
  4. KW 2449
  5. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. PCDH11X
  2. ANKRD2
  3. FUBP3
  4. CAMK1
  5. NR5A1
Explore Knockdown Atlas Results

Curated Studies

Most Correlated Studies

  1. Neuroblastoma SKNDZ cells overexpressing MIR-125-B2
  2. Neural development of iPSCs derived from Autistic patients with BCKD-kinase mutations
  3. L1000 CMAP - Pancreatic cancer YAPC.311 cells with CRISPR-targeted gene knockouts
  4. L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
  5. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Building a statistical model for predicting cancer genes.
  2. Involvement of CD45 in central nervous system myelination.
  3. Regulation of the human c-fes protein tyrosine kinase (p93c-fes) by its src homology 2 domain and ma…
  4. The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autoph…
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Clinical Trials

Most Relevant Clinical Trials

  1. Pertuzumab in First Line Treatment of HER2-positive Metastatic Breast Cancer Patients
  2. Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer
  3. Trial to Evaluate the Therapeutic Benefit of Fulvestrant in Combination With ZACTIMA in Postmenopaus…
  4. Expression Profile of ERK5 and PKM2 Kinases in Neuroinflammatory Diseases.
  5. Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With…
Explore Clinical Trials Results
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