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heterochromatin organization
(biogroup)
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General Info
Body Atlas
Most Correlated Tissues
Stomach
Skin
Globus pallidus
Thymus gland
Smooth muscle
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Intestinal infection due to Pseudomonas
Helicobacter pylori gastrointestinal tract infection
Gastrointestinal hemorrhage
Alpha-1-antitrypsin deficiency
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Pharmaco Atlas
Most Correlated Compounds
GW9508
CGP 60474
flavopiridol
((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
AZD4547
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Knockdown Atlas
Most Correlated Gene Perturbations
bgcn
os
Rela
CASC15
GNAS
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
Prostate cancer cell lines - miRNA expression profiling
Lung tissues from chronic obstructive pulmonary disease patients
L1000 CMAP - Kidney epithelial HA1E.311 cells with CRISPR targeted gene knockouts
Functional constraints on the integrity of an ultra conserved region in Drosophila
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Literature
Most Relevant Literature
Drugs affecting prelamin A processing: effects on heterochromatin organization.
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organ…
The nucleoplasmin homolog NLP mediates centromere clustering and anchoring to the nucleolus.
High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3-9 double mut…
Induced pluripotent stem-induced cells show better constitutive heterochromatin remodeling and devel…
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Clinical Trials
Most Relevant Clinical Trials
Pathology of Helicases and Premature Aging: Study by Derivation of hiPS
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With …
Preimplantation Genetic Screening in Patients With Male Factor Infertility
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