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rs2300478
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SLC12A1
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insulin-like growth factor II binding
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Tonsil
Substantia nigra reticulata
Urethra
Globus pallidum external
Globus pallidus
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Disease Atlas
Most Correlated Diseases
Alpha-1-antitrypsin deficiency
Disorder of digestive system
Retinal detachment
Sendai virus infection
Disorder of lung
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Pharmaco Atlas
Most Correlated Compounds
Tie2 kinase inhibitor
CP 724714
I-BET 151
Benzothiazoles
DCC-2036
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Knockdown Atlas
Most Correlated Gene Perturbations
SULF1
GPRC5A
POU3F1
EDA
ACVR1
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose 6-phosphate/in…
Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor r…
Merkel cell carcinoma expresses K homology domain-containing protein overexpressed in cancer similar…
Measurement of insulin-like growth factor (IGF)-II binding to purified IGF binding proteins 1-6: com…
Insulin-like growth factor II binding and action in human fetal fibroblasts.
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Clinical Trials
Most Relevant Clinical Trials
Study of Recombinant Human Insulin-Like Growth Factor I in Patients With Severe Insulin Resistance
Growth Hormone Feedback to Insulin-like Growth Factor-I (IGF-1) and Oral Glucose Tolerance Test (OGT…
Role of IMP3 Expression in Colorectal Carcinoma: An Immunohistochemical Study
A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Ped…
Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insuli…
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