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p53 binding
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Summary
General Info
Body Atlas
Most Correlated Tissues
No tissues found
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Helicobacter pylori gastrointestinal tract infection
Perforation of tympanic membrane
Injury of eye region
Barrett's esophagus
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Pharmaco Atlas
Most Correlated Compounds
CGP 60474
flavopiridol
AT 7519
combretastatin A-4
OTS-167
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Knockdown Atlas
Most Correlated Gene Perturbations
Idd1
Idd5
DIDO1
FUBP3
IRF7
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Curated Studies
Most Correlated Studies
miRNA expression profiles from osteosarcoma samples and cell lines
Tumor formation by ATG5 KO cells
Follicular fluid miRNA profiles during the development of the oocyte
Lung adenocarcinoma and adjacent normal tissue miRNA expression profiles
Adult T-cell Leukemia (ATL) cells and in Normal CD4+ T-cells miRNA expression
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Literature
Most Relevant Literature
p53 binds the mdmx mRNA and controls its translation.
Tumor-suppressor p53 specifically binds to miR-29c-3p and reduces ADAM12 expression in hepatocellula…
Computational studies suggest compounds restoring function of p53 cancer mutants can bind SARS-CoV-2…
Two p53 tetramers bind one consensus DNA response element.
Wild-type p53 binds to MYC promoter G-quadruplex.
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Clinical Trials
Most Relevant Clinical Trials
CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
Phase II Study of Metastatic Cancer That Overexpresses P53 Using Lymphodepleting Conditioning Follow…
Arsenic Trioxide in Recurrent and Metastatic Ovarian Cancer and Endometrial Cancer With P53 Mutation
Arsenic Trioxide in Refractory Solid Tumors With Rescuable p53 Mutation
Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations
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