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QuickView for 3',5'-cyclic-nucleotide phosphodiesterase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Heart
  2. Oral mucosa
  3. Parietal lobe
  4. Heart atrium
  5. Nipple cross-section
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Disease Atlas

Most Correlated Diseases

  1. Festuca arundinacea poisoning
  2. Ulceration of intestine
  3. Chlamydial infection
  4. Alpha-1-antitrypsin deficiency
  5. Disorder of digestive system
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Pharmaco Atlas

Most Correlated Compounds

  1. tivozanib
  2. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  3. FR 180204
  4. BMS 777607
  5. ARQ 197
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. SULF1
  2. CAMK1
  3. ENPP2
  4. PDE6B
  5. DMRT1
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Prostate cancer PC3.101 cells with CRISPR-targeted gene knockouts
  2. L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
  3. Reprogramming of fibroblasts into embryonic Sertoli-like cells
  4. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
  5. L1000 CMAP - Pancreatic cancer YAPC.311 cells with CRISPR-targeted gene knockouts
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Literature

Most Relevant Literature

  1. Characterization of 3',5' cyclic nucleotide phosphodiesterase activity in Y79 retinoblastoma cells: …
  2. Induction of cyclic AMP and cyclic GMP 3':5'-cyclic nucleotide phosphodiesterase activities in neuro…
  3. Activation of rat cerebral cortical 3',5'-cyclic nucleotide phosphodiesterase activity by gangliosid…
  4. Characterization of 3':5' cyclic nucleotide phosphodiesterase activities of mouse neuroblastoma N18T…
  5. 3':5'-cyclic nucleotide phosphodiesterase activity in mammalian tissues.
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Clinical Trials

Most Relevant Clinical Trials

  1. Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) as Medical Expulsive Therapy in Distal Ureteral …
  2. PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhi…
  3. Appetite Suppression Effects of an Herbal Combination of Yerba maté, Guarana, Damiana (YGD), and 12 …
  4. Treprostinil Combined With Tadalafil for Pulmonary Hypertension
  5. In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human …
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