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Correlation Engine 2.0
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(e.g. Aspirin, rs3825942, PRKCA, Metabolism of xenobiotics, Influenza, Intestine)
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QuickView for proteoglycan binding (biogroup)


Body Atlas

Most Correlated Tissues

  1. Synovial membrane
  2. Pericardium
  3. Adipose tissue subcutaneous
  4. Cerebellar hemisphere
  5. Cerebellar vermis
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Disease Atlas

Most Correlated Diseases

  1. Duchenne muscular dystrophy
  2. Fibrosis of lung
  3. Acute hepatic failure
  4. Alpha-1-antitrypsin deficiency
  5. Hepatic failure
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Pharmaco Atlas

Most Correlated Compounds

  1. CGP 60474
  2. ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
  3. flavopiridol
  4. BMS 387032
  5. AT 7519
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. 491333
  2. MAST4
  3. YME1L1
  4. NR5A1
  5. PPP2R2C
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  4. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  5. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer.
  2. Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate.
  3. ADAMTS4 Enhances Oligodendrocyte Differentiation and Remyelination by Cleaving NG2 Proteoglycan and …
  4. Identification of proteoglycan-binding proteins.
  5. Internalization and trafficking of cell surface proteoglycans and proteoglycan-binding ligands.
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Clinical Trials

Most Relevant Clinical Trials

  1. Investigation on Differences in Skin Sodium Content Between Normal Subjects and ICU-patients
  2. NSPT On Vitronectin And Fetuin-A Levels In Patients With Periodontitis And Coronary Artery Disease
  3. The Effect of E-EPA on Circulating LDL and Plasma Lipid Metabolism
  4. The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk
  5. Efficacy and Safety of Liposomal Lactoferrin in COVID-19 Patients With Mild-to-Moderate Disease and …
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