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SH2 domain binding
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Summary
General Info
Body Atlas
Most Correlated Tissues
Spleen
Lymph nodes
Tonsil
Frontal cortex
Accumbens
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Protozoan infection
Chlamydial infection
Alpha-1-antitrypsin deficiency
Poisoning by drug AND/OR medicinal substance
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Pharmaco Atlas
Most Correlated Compounds
CP 724714
CGP 60474
AS 601245
AT 7519
A 443654
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR122
NOP2
MTTP
MAST4
NR5A1
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Curated Studies
Most Correlated Studies
Kidneys from male C57BL6 mice 28 days after left proximal ureter ligations
Carotid arteries from atherogenic ApoE knockout mice with carotid artery injury
Tumor formation by ATG5 KO cells
Glomerulonephrotic and healthy tissue from C57BL6.MRLc1 congenic mice
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Structure Determination of SH2-Phosphopeptide Complexes by X-Ray Crystallography: The Example of p12…
Lipid Binding of SH2 Domains.
Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2.
Engineering SH2 Domains with Tailored Specificities and Affinities.
Measuring Protein Tyrosine Phosphatase Activity Dependent on SH2 Domain-Mediated Regulation.
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Clinical Trials
Most Relevant Clinical Trials
Phase II Study of Isoflavone G-2535 (Genistein) in Patients With Bladder Cancer
Can Dormant Perimenopausal Ovarian Follicles Become FSH Responsive?
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