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hexosaminidase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Occipital lobe
Testes
Placenta
Substantia nigra reticulata
Hypothalamus
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Disease Atlas
Most Correlated Diseases
Injury of external ear
Stachybotryotoxicosis
Alpha-1-antitrypsin deficiency
Tay-Sachs disease
Pyloric ulcer
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Pharmaco Atlas
Most Correlated Compounds
NVP-AEW541
Apitolisib
CGP 60474
PI103
AT 7519
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Knockdown Atlas
Most Correlated Gene Perturbations
PPP2R2C
MUTYH
NR5A1
F2R
KDELR1
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosamini…
Increased hexosaminidase activity in antipsychotic-induced extrapyramidal side effects: possible ass…
N-acetyl-beta-hexosaminidase activity in asthma.
Juvenile-onset motor neuron disease caused by novel mutations in β-hexosaminidase.
Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy.
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Clinical Trials
Most Relevant Clinical Trials
The Impact of Lung Cancer-derived Fibroblasts on Mast Cells Activation
A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis
Gene Therapy for Tay-Sachs Disease
A Natural History of Late Onset Tay-Sachs Disease
Registry Gangliosidoses
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