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lysosomal lumen
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Summary
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Body Atlas
Most Correlated Tissues
Lung
Microglial cell
Duodenum
Skeletal muscle
Fetal brain
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Disease Atlas
Most Correlated Diseases
Protozoan infection
Duchenne muscular dystrophy
Acute hepatic failure
Bacterial infection of skin
Drug resistance
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Most Correlated Compounds
CGP 60474
OTS-167
dinaciclib
flavopiridol
AT 7519
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Knockdown Atlas
Most Correlated Gene Perturbations
AURKB
TSC1
MNDA
FGF13
RPS6
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
Cardiomyocytes from embryonic stem cells treated with various concentrations of doxorubicin
L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Interpretation of bafilomycin, pH neutralizing or protease inhibitor treatments in autophagic flux e…
The ubiquitin code and its decoding machinery in the endocytic pathway.
A weak base-generating system suitable for selective manipulation of lysosomal pH.
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy.
Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin.
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Clinical Trials
Most Relevant Clinical Trials
Incidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features
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