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QuickView for purine-containing compound salvage (biogroup)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (CD4+) of peripheral blood
  2. Cerebellum
  3. Myometrium
  4. Hematopoietic stem cell of bone marrow
  5. Monocyte of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Social environment related disease
  2. Vesicular stomatitis Indiana virus disease
  3. Listeriosis
  4. Lesch-Nyhan syndrome
  5. Purine-nucleoside phosphorylase deficiency
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Pharmaco Atlas

Most Correlated Compounds

  1. 5-(6)-carboxyfluorescein diacetate succinimidyl ester
  2. CGP 60474
  3. A-66
  4. OTS-167
  5. AT 7519
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. Mir10a
  2. HDAC11
  3. RPIA
  4. CYP2C19
  5. Ikzf1
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
  2. The Immunological Genome Project - Immune cell lineage differentiation and maturation
  3. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  4. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  5. L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Purine salvage in Leishmania: complex or simple by design?
  2. Borrelia burgdorferi harbors a transport system essential for purine salvage and mammalian infection…
  3. Helicobacter pylori relies primarily on the purine salvage pathway for purine nucleotide biosynthesi…
  4. Purine Salvage Pathway in Mycobacterium tuberculosis.
  5. Inhibitors of the purine salvage pathway: a valuable approach for antiprotozoal chemotherapy?
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Clinical Trials

Most Relevant Clinical Trials

  1. Bendamustine in Combination With Ofatumumab, Carboplatin and Etoposide for Refractory or Relapsed Ag…
  2. Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents…
  3. Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia
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