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protein destabilization
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Body Atlas
Most Correlated Tissues
Penis
Transverse colon
Fallopian tube
Adrenal gland cortex
Joint synovium
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Disease Atlas
Most Correlated Diseases
Bacterial pneumonia
Alpha-1-antitrypsin deficiency
Pyloric ulcer
Vesicular stomatitis Indiana virus disease
Multiple-resistant Staphylococcus aureus infection
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Pharmaco Atlas
Most Correlated Compounds
flavopiridol
CGP 60474
AT 7519
A 443654
ALW-II-49-7
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Knockdown Atlas
Most Correlated Gene Perturbations
PCDH11X
FUBP3
PPP2R2C
IRF7
PCDH11X
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Curated Studies
Most Correlated Studies
Glomerulonephrotic and healthy tissue from C57BL6.MRLc1 congenic mice
Tumor formation by ATG5 KO cells
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Adipocyte ASC cells treated with small molecule perturbagens
L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Structural and energetic basis of protein kinetic destabilization in human phosphoglycerate kinase 1…
Tuning protein autoinhibition by domain destabilization.
Synaptic protein degradation underlies destabilization of retrieved fear memory.
Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation rep…
von Hippel-Lindau protein promotes Skp2 destabilization on DNA damage.
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Clinical Trials
Most Relevant Clinical Trials
Effect of Dietary Protein on the Regulation of Exosome microRNA Expression in Patients With Insulin …
Analysis of Post-Translational Modifications of a Critical Protein Implicated in Amyotrophic Lateral…
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic
A Trial Of PF-04856884 In Patients With Recurrent Glioblastoma
Efficacy of ADW S-100 Ionized Water Nasal Spray in Decreasing SARS-Cov-2 Viral Load.
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