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deoxycytidine deaminase activity
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Summary
General Info
Body Atlas
Most Correlated Tissues
Bone marrow
Leukocyte (polymorphonuclear) of peripheral blood
Basophil of peripheral blood
Monocyte of peripheral blood
Macrophage of peripheral blood
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Disease Atlas
Most Correlated Diseases
Spotted fevers
Eczema
Disease due to Enterovirus
Injury of integument
Ebola virus disease
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Pharmaco Atlas
Most Correlated Compounds
sitagliptin
roscovitine
((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
mono-(2-ethylhexyl)phthalate
SB939 compound
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Knockdown Atlas
Most Correlated Gene Perturbations
HRAS
NUP85
CPEB1
TLK2
FSHR
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Curated Studies
Most Correlated Studies
L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (1 of 2)
L1000 CMAP - T-cell ALL JURKAT cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP Breast cancer MCF7 cells with gene overexpression perturbations
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Analysis of deoxycytidine (dC) deaminase activity in herpes simplex virus-infected or HSV TK-transfo…
Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with…
Specific selection of deoxycytidine kinase mutants with tritiated deoxyadenosine.
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Clinical Trials
Most Relevant Clinical Trials
A Multi-Histology Phase II Study of 5-Fluoro-2'-Deoxycytidine With Tetrahydrouridine (FdCyd + THU)
Imaging Study for FdCyd and THU Cancer Treatment
5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer
Decitabine in Treating Children With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphobl…
FdCyd and THU for Advanced Solid Tumors
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