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QuickView for protein deacetylase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Pericardium
  2. Joint synovium
  3. Adipose tissue
  4. Thymus gland
  5. Duodenum
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Disease Atlas

Most Correlated Diseases

  1. Pyloric ulcer
  2. Periodontitis
  3. Drug resistance
  4. COVID-19
  5. Alpha-1-antitrypsin deficiency
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Pharmaco Atlas

Most Correlated Compounds

  1. N-(5-(4-bromophenyl)-6-(2-(5-bromopyrimidin-2-yloxy)ethoxy)pyrimidin-4-yl)-N'-propylaminosulfonamide
  2. GSK-1059615
  3. BS-181
  4. CGP 60474
  5. OTS-167
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. CCDC170
  2. GPRC5B
  3. TLK2
  4. NCL
  5. LCK
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Curated Studies

Most Correlated Studies

  1. Airway epithelium and blood single cell markers in COVID-19
  2. A single cell analysis of human fetal bone marrow 12-19 weeks post fertilization
  3. A single cell analysis of adult human skin
  4. Tabula sapiens - single cell gene expression across human tissues and organsystems
  5. A single cell analysis of human CD34+ fetal bone marrow, fetal liver, and cord blood
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Literature

Most Relevant Literature

  1. Pre-B-cell colony-enhancing factor regulates NAD+-dependent protein deacetylase activity and promote…
  2. Emerging beneficial roles of sirtuins in heart failure.
  3. Peroxisome proliferator activated receptor α ligands as anticancer drugs targeting mitochondrial met…
  4. Overexpression of SIRT6 in porcine fetal fibroblasts attenuates cytotoxicity and premature senescenc…
  5. Cloning and characterization of NAD-dependent protein deacetylase (Rv1151c) from Mycobacterium tuber…
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Clinical Trials

Most Relevant Clinical Trials

  1. Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours
  2. Anti-PD-1 Antibody Combined With Histone Deacetylase Inhibitor in Patients With Advanced Cervical Ca…
  3. Phase II Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/…
  4. A Study of the Histone-deacetylase Inhibitor JNJ-26481585 in Patients With Advanced or Refractory Le…
  5. Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwann…
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