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Correlation Engine 2.0
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QuickView for interleukin-6-mediated signaling pathway (biogroup)


Body Atlas

Most Correlated Tissues

  1. Saphenous vein
  2. Aorta
  3. Adipose tissue
  4. Pericardium
  5. Fetal brain
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Disease Atlas

Most Correlated Diseases

  1. Contact dermatitis
  2. Alpha-1-antitrypsin deficiency
  3. Pyloric ulcer
  4. Legionella infection
  5. Bacterial infection due to Bacillus
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Pharmaco Atlas

Most Correlated Compounds

  1. combretastatin A-4
  2. brivanib alaninate
  3. epothilone B
  4. 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  5. CP 466722
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. RIOK2
  2. PCDH11X
  3. LAT
  4. NCL
  5. PPRC1
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  2. L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
  3. L1000 CMAP - Non-small cell lung cancer A549.311 cells with CRISPR targeted gene knockouts
  4. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
  5. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3.
  2. The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signalin…
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Clinical Trials

Most Relevant Clinical Trials

  1. Association and Mechanism Between Cyclooxygenase-2 and Interleukin-6 in Gastric Cancer
  2. Androgenetic Alopecia and the JAK-STAT Pathway
  3. IL-2 Signaling and Polarization of Regulatory LBs: Involvement in Multiple Sclerosis
  4. Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CN…
  5. Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 …
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