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QuickView for tetrahydrobiopterin binding (biogroup)


Body Atlas

Most Correlated Tissues

  1. Midbrain
  2. Pons
  3. Thyroid gland
  4. Extraocular muscle
  5. Breast tissue
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Disease Atlas

Most Correlated Diseases

  1. Tuberculin reaction
  2. Pyloric ulcer
  3. Pyloric stenosis
  4. Vesicular stomatitis Indiana virus disease
  5. 11p partial monosomy syndrome
Explore Disease Atlas Results

Pharmaco Atlas

Most Correlated Compounds

  1. 5,6,7,8-tetrahydrobiopterin
  2. alpha-Methyltyrosine
  3. CGP 60474
  4. Cytochalasin B
  5. A 443654
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. EFCAB2
  2. MAML3
  3. PRMT6
  4. BMPR2
  5. SUMO2
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Curated Studies

Most Correlated Studies

  1. Drug target sets for approved compounds
  2. Mouse Phenotypes - Diabetes insipidus
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  4. OMIM - Vascular disease
  5. Primordial germ cells from embryonic stem cells by SOX17 and BLIMP1 overexpression or by cytokines
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Literature

Most Relevant Literature

  1. Interaction between neuronal nitric-oxide synthase and tetrahydrobiopterin revisited: studies on the…
  2. Tyrosine hydroxylase activity is regulated by two distinct dopamine-binding sites.
  3. Aromatic amino acid hydroxylase genes and schizophrenia.
  4. A proximal tryptophan in NO synthase controls activity by a novel mechanism.
  5. Specificity and binding capacity of human blood serum for tetrahydropterins.
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Clinical Trials

Most Relevant Clinical Trials

  1. Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mel…
  2. Local Vasoconstriction in Postural Tachycardia Syndrome
  3. The Effectiveness of Kuvan in Amish PKU Patients
  4. Reverse Transcriptase Inhibitors in Aicardi Goutières Syndrome
  5. The Effects of CGMP in Children and Adults With PKU
Explore Clinical Trials Results
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