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BRCA1-A complex
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General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Subthalamic nucleus
Stomach cardiac
Nodose nucleus
Testes
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Disease Atlas
Most Correlated Diseases
Disorder of uterus
Alpha-1-antitrypsin deficiency
Disorder of digestive system
Musculoskeletal fibromatosis
Festuca arundinacea poisoning
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Pharmaco Atlas
Most Correlated Compounds
bromohydrin pyrophosphate
Phorbol Esters
Antigens, Neoplasm
plastochromanol 8
PHA 739358
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Knockdown Atlas
Most Correlated Gene Perturbations
hsa-miR-31-5p
DIDO1
BABAM2
RNR1
AURKB
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Curated Studies
Most Correlated Studies
NSCLC PC9 cells selected for gefitinib sensitivity or resistance treated with EGF and gefitinib
The Immunological Genome Project - Immune cell lineage differentiation and maturation
Multiple myeloma MM.1S and U266 cells treated with PIM2 kinase inhibitor JP11646
Lower motor neurons laser-microdissected from spinal cords of sporadic or mutant TARDBP ALS patients
B lymphoblast TK6 cells treated with 15 genotoxic carcinogens
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Literature
Most Relevant Literature
Folliculin deficient renal cancer cells exhibit BRCA1 A complex expression impairment and sensitivit…
Mislocalization of BRCA1-complex due to ABRAXAS Arg361Gln mutation.
MLN4924 suppresses the BRCA1 complex and synergizes with PARP inhibition in NSCLC cells.
Genetic evaluation of BRCA1 associated a complex genes with triple-negative breast cancer susceptibi…
Role of MERIT40 in stabilization of BRCA1 complex: a protein-protein interaction study.
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Clinical Trials
Most Relevant Clinical Trials
Promoting Men's Adherence to BRCA1/2 Germline Genetic Testing
Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast C…
A Study to Compare Two Surgical Procedures in Women With BRCA1 Mutations to Assess Reduced Risk of O…
Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or…
Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Neural Reward System in …
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