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regulation of DNA repair
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General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Testes
Endometrium
Vena cava
Subthalamic nucleus
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Disease Atlas
Most Correlated Diseases
Alpha-1-antitrypsin deficiency
Disorder of digestive system
Listeriosis
Zika virus disease
Perforation of tympanic membrane
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Pharmaco Atlas
Most Correlated Compounds
Butylhydroxybutylnitrosamine
enterotoxin F, Staphylococcal
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
KW 2449
BMS 777607
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR125B2
DNAJC2
NRF1
NOP2
NOP2
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Curated Studies
Most Correlated Studies
Induction of pluripotency in mouse somatic cells with novel factors
The Immunological Genome Project - Immune cell lineage differentiation and maturation
Neural development of iPSCs derived from Autistic patients with BCKD-kinase mutations
Retinoic acid regulation of stage-dependent gene expression in Sertoli cells
BV-2 microglial cells treated with curcumin, LPS or both treatments
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Literature
Most Relevant Literature
TRIP13 regulates DNA repair pathway choice through REV7 conformational change.
βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1.
RNF168-mediated H2A neddylation antagonizes ubiquitylation of H2A and regulates DNA damage repair.
Regulation of DNA repair by S-nitrosylation.
Androgen receptor signaling regulates DNA repair in prostate cancers.
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Clinical Trials
Most Relevant Clinical Trials
A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate C…
BRCA1-associated DNA Repair Dysfunction in Patients With Early Triple Negative Breast Cancer Treated…
A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001…
The Trial Comparing Dose-dense AC-T With TP as Adjuvant Therapy for TNBC With Homologous Recombinati…
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cance…
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