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cytolytic granule
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Summary
General Info
Body Atlas
Most Correlated Tissues
Whole blood
Basophil of peripheral blood
Lung
Ovary
Mononuclear cell of peripheral blood
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Disease Atlas
Most Correlated Diseases
Viral carditis
Protozoan infection
Vesicular stomatitis Indiana virus disease
Contact dermatitis
Cytomegalovirus infection
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Podophyllotoxin
Quinacrine
valrubicin
tioconazole
SGI 1776
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Most Correlated Gene Perturbations
ASNSD1
TLX3
TNFRSF21
TLK2
PPP2R2C
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Curated Studies
Most Correlated Studies
L1000 CMAP - Skeletal muscle SKL.C cells treated with small molecule perturbagens
Lymphoma (4 types) and B-cell purified subpopulation gene expression profiling
L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
Whole blood mRNA expression profiling in neonatal sepsis
L1000 CMAP - Melanoma A375 cells with CRISPR-targeted gene knockouts
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Literature
Most Relevant Literature
Role of the inflammatory protein serine protease inhibitor Kazal in preventing cytolytic granule gra…
Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin alp…
Elevated serum granulysin and its clinical relevance in mature NK-cell neoplasms.
Myosin IIA is required for cytolytic granule exocytosis in human NK cells.
Chimeric antigen receptor-redirected T cells display multifunctional capacity and enhanced tumor-spe…
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Clinical Trials
Most Relevant Clinical Trials
Allogeneic NK Cell ("SMT-NK") in Combination With Pembrolizumab in Advanced Biliary Tract Cancer
Granzymes and Perforin at the Onset of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
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