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GTP cyclohydrolase activity
(biogroup)
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General Info
Body Atlas
Most Correlated Tissues
Ileum mucosa
Liver
Myeloid cells of peripheral blood
T Lymphocyte (regulatory) of peripheral blood
Monocyte of peripheral blood
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Disease Atlas
Most Correlated Diseases
Classical phenylketonuria
Alpha-1-antitrypsin deficiency
Hyperphenylalaninemia
Disorder of digestive system
Brucellosis
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Pharmaco Atlas
Most Correlated Compounds
enrofloxacin
Sumatriptan
Lincomycin
Cyclandelate
Interleukin-1
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Knockdown Atlas
Most Correlated Gene Perturbations
Stat3
NAMPT
EZR
SOD2
ACVR1
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Curated Studies
Most Correlated Studies
OMIM - Dystonia
L1000 CMAP - T-ALL Jurkat cells with shRNA-mediated gene knockdown
L1000 CMAP Osteosarcoma U-2 OS cells with gene overexpression perturbations
L1000 CMAP Breast cancer MCF7 cells with gene overexpression perturbations
Dorsal root ganglia gene expression at 2 days, 2 weeks, and 20 weeks post-spinal nerve ligation
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Literature
Most Relevant Literature
GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major …
Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dop…
Correlation of guanosine triphosphate cyclohydrolase activity and the synthesis of pterins in Drosop…
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Clinical Trials
Most Relevant Clinical Trials
A Study of PTC923 in Participants With Phenylketonuria
A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria
A Study of CNSA-001 in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalan…
Managing Endothelial Dysfunction in Critically Ill COVID-19 Patients at LAUMCRH
Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC
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