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pyrimidine nucleoside salvage
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Oral mucosa
Vulva
Pharyngeal mucosa
Monocyte of peripheral blood
Myeloid cells of peripheral blood
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Disease Atlas
Most Correlated Diseases
Alpha-1-antitrypsin deficiency
Disorder of digestive system
Placental insufficiency
Injury of integument
Cryptococcosis
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Pharmaco Atlas
Most Correlated Compounds
HG-9-91-01
AZD4547
valrubicin
Apitolisib
5-(6)-carboxyfluorescein diacetate succinimidyl ester
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Knockdown Atlas
Most Correlated Gene Perturbations
ZAP1
AURKB
ROR1
ECH1
LAT
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Umbilical vein endothelial HUVEC cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Identification and characterization of mitochondrial factors modulating thymidine kinase 2 activity.
Inhibition of thymidine phosphorylase expression by using an HSP90 inhibitor potentiates the cytotox…
Pyrimidine nucleoside salvage confers an advantage to Xenorhabdus nematophila in its host interactio…
Targeting platelet-derived endothelial cell growth factor/thymidine phosphorylase for cancer therapy…
5'-O-tritylated nucleoside derivatives: inhibition of thymidine phosphorylase and angiogenesis.
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Clinical Trials
Most Relevant Clinical Trials
Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome
Ticagrelor And PrEconditioning in Patients With coronaRy Artery diSease
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