QuickView for MLL1 complex (biogroup)

1. Neural development of iPSCs derived from Autistic patients with BCKD-kinase mutations
2. GSK cancer cell line transcript profiling
3. Testis and ovary subsets from 3 embryonic time points
4. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
5. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens

1. Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation.
2. Phase separation promotes a highly active oligomeric scaffold of the MLL1 core complex for regulatio…
3. CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex.
4. Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
5. Inhibiting an RBM39/MLL1 epigenomic regulatory complex with dominant-negative peptides disrupts canc…

There were no clinical trials for MLL1 complex