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B cell negative selection
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Colon
Small intestine
Colon mucosa
Ileum mucosa
B lymphocyte (IgM memory) of spleen
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Disease Atlas
Most Correlated Diseases
Tuberculin reaction
Irritable bowel syndrome
Intestinal infectious disease
Liver fluke infection
Duchenne muscular dystrophy
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Pharmaco Atlas
Most Correlated Compounds
Propylene Glycol
glycidol
BRL 37344
Antipyrine
E6 protein, Human papillomavirus type 18
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR142
ZW10
KCNA1
BAK1
DCAF1
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Curated Studies
Most Correlated Studies
NSCLC PC9 cells selected for gefitinib sensitivity or resistance treated with EGF and gefitinib
Embryonic fibroblasts from Bax/Bak double knock-out mice resistant or sensitive to C12
Peripheral blood cells of rheumatoid arthritis patients treated with infliximab
L1000 CMAP - Adipose MSC ASC52telo cells with shRNA-mediated gene knockdown
L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
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Literature
Most Relevant Literature
B cells participate in thymic negative selection of murine auto-reactive CD4+ T cells.
Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.
Differential c-Myc responsiveness to B cell receptor ligation in B cell-negative selection.
Does CD40 ligation induce B cell negative selection?
Enhanced selection of high affinity DNA-reactive B cells following cyclophosphamide treatment in mic…
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Clinical Trials
Most Relevant Clinical Trials
This is a Phase 1 Study of MH048 in Patients With Selected Relapsed/Refractory B-cell Malignancies
B-Lymphocyte Stimulator (BLyS) To Treat Selective IgA Deficiency
Idelalisib Post Allogeneic Hematopoietic Stem Cell Transplant (HSCT) in B Cell Derived Malignancies
A Study of HSK29116 in Adults With Relapsed/Refractory B-cell Malignancies
A Study of Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies
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