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MAP kinase kinase kinase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Small intestine
Jejunum
Fetal brain
Colon
Hypothalamus
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Disease Atlas
Most Correlated Diseases
Sepsis due to coagulase negative Staphylococcus
Multiple organ dysfunction syndrome
Abscess
Pyloric ulcer
Peritoneal foreign body
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Pharmaco Atlas
Most Correlated Compounds
GSK690693
JM 3100
OTS-167
GSK-1059615
CGP 60474
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR122
PPP2R2C
POLH
BPHL
NOP2
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Curated Studies
Most Correlated Studies
Liver gene expression in mice exposed daily to benzo[a]pyrene (BaP)
Carotid arteries from atherogenic ApoE knockout mice with carotid artery injury
Dicer1 knockout gene expression during Schwann cell development
Kidneys from male C57BL6 mice 28 days after left proximal ureter ligations
microRNA expression in cells resistant to endocrine therapy or in LTED breast cancer cell lines
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Literature
Most Relevant Literature
Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells, Role of…
Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-tr…
Activation of (His)6-Raf-1 in vitro by partially purified plasma membranes from v-Ras-transformed an…
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Clinical Trials
Most Relevant Clinical Trials
P38 Mitogen-activated Protein (Map) Kinase Inhibitor (SB-681323)Study In Patients With Neuropathic P…
Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Hu…
Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With…
A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer'…
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzhe…
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